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New England Biolabs
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Monobind
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Boston Scientific Corporation
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Noyes Inc
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ALPCO
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Monobind
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LSI Medience Corporation
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New England Biolabs
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Arbor Assays
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Aslan Pharmaceuticals
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Journal: bioRxiv
Article Title: Noncoding and Coding Mechanisms of Aging Heart Failure with Preserved Ejection Fraction with Thyroid Dysfunction
doi: 10.1101/2025.02.04.636476
Figure Lengend Snippet: Serum (A) total T3 and (B) total T4 levels in 5 mo and 13 mo male WT control, ZSF1 lean control, and ZSF1 obese rats; Serum (C) total T3 and (D) total T4 levels in 5 mo, 13 mo and 20 mo male WT control and ZSF1 lean control. All values are analyzed using Two-way ANOVA (TWA) and presented as means ± standard deviation; WT: Wild Type; T4: Thyroxine; T3: Triiodothyronine; *p<0.05; ****p<0.0001 vs 5 mo WT control (TWA); #### p < 0.0001 vs 5 mo ZSF1 lean control (TWA); ΦΦ p<0.01vs 13 mo ZSF1 lean control (TWA); θ p<0.05 vs. 13 mo obese HFpEF (t-test).
Article Snippet: Serum total T3 (tT3) and total
Techniques: Control, Standard Deviation
Journal: iScience
Article Title: TRIAC disrupts cerebral thyroid hormone action via negative feedback and heterogenous distribution among organs
doi: 10.1016/j.isci.2023.107135
Figure Lengend Snippet: TRIAC effects on the hypothalamus-pituitary-thyroid axis in hypothyroid mice (A–D) Serum levels of 3,3′,5,5′-tetraiodothyronine (T4), 3,3′,5-triiodothyronine (T3), TRIAC, and thyroid-stimulating hormone (TSH). (E) Gross appearance of thyroid glands. The scale on the ruler is 1 mm. (F) Thyroid gland size was measured as thyroid area on photograph. (G–J) Histological images of thyroid glands stained using hematoxylin and eosin. Vehicle, PTU, PTU + TRIAC, n = 6 each; PTU + LT3, n = 5. BLQ, below the limit of quantitation. Concentrations of PTU, LT3, and TRIAC used were 100 μg/mL, 0.1 μg/mL, and 0.1 μg/mL, respectively. Data are represented as means ± SEM. Statistical analyses were performed using Student’s t -test for vehicle vs. PTU and the p value is presented as †††p < 0.001. ANOVA followed by the Tukey-Kramer test was used for comparisons among PTU, PTU + LT3, and PTU + TRIAC experiments and the p value is presented as ∗∗p < 0.01, and ∗∗∗p < 0.001.
Article Snippet: We measured
Techniques: Staining, Quantitation Assay